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Erling Haaland scored his 34th goal for club and country this season to give Manchester City a 2-1 win at Real Madrid on Wednesday as Arsenal maintained their perfect group stage record with a 3-0 victory at Club Brugge.
It was a second successive home defeat for Real following their 2-0 reverse against Celta Vigo at the weekend and heaped more pressure on coach Xabi Alonso, whose side have won just two of their last eight in all competitions.
For Haaland, though, this was a 21st goal in 21 City games this season and a 51st in 50 Champions League starts, while Nico O'Reilly scored his first goal in the competition.
Rodrygo gave Real, who were missing Kylian Mbappe, the lead just before the half-hour mark with a crisp shot across Gianluigi Donnarumma into the far corner.
But academy product O'Reilly equalised just seven minutes later, reacting quickest to prod home the loose ball from inside the six-yard box after Thibaut Courtois had saved Josko Gvardiol's header.
And Haaland was able to fire City in front from the penalty spot on 43 minutes after VAR intervened to punish Antonio Rudiger for wrestling the Norwegian forward to the ground to prevent him reaching a cross.
It could have been worse for Real but Courtois redeemed himself somewhat for flapping at Gvardiol's header with a crucial double save to deny Haaland and Rayan Cherki in quick succession as the half drew to a close.
It was a breathless end-to-end second half and Jude Bellingham could have done better than chip over the bar with only Donnarumma to beat, while Courtois made a fingertip save to deny Jeremy Doku.
Vinicius Jr. had a late chance to equalise but skied his volley after Donnarumma had come for and missed an inswinging corner.
Substitute Endrick also clipped the top of the bar with a header as Real pushed for a late equaliser.
- Arsenal on brink of last 16 -
Noni Madueke's double helped Arsenal win a sixth straight Champions League match this season and close in on the last 16.
The Premier League leaders already have more points (18) than was needed last season to secure a top eight spot and direct qualification for the last 16, and they have two matches still to come.
Madueke's two goals could not have been more different.
The first was a wonder goal in which he beat two players and thrashed in a long-range strike.
For the second he was teed up by Martin Zubimendi for a simple finish.
Brugge had put the Gunners under fierce first-half pressure but they crumbled after the second goal as Gabriel Martinelli added to their misery, bending the ball around the goalkeeper from outside the box.
Elsewhere, reigning champions Paris Saint-Germain were held to a 0-0 draw at Athletic Bilbao but stayed third, behind only Arsenal and Bayern Munich, with City fourth.
Weston McKennie and Jonathan David scored the goals as Juventus overcame Pafos 2-0, while Bayer Leverkusen and Newcastle shared a 2-2 draw, as did Borussia Dortmund and Bodo/Glimt.
Goals from Richard Rios and Leandro Barreiro gave Jose Mourinho's Benfica a 2-0 win over Antonio Conte's Napoli in a battle of the former Chelsea bosses.
Oscar Gloukh scored a brace as Ajax hit three late goals to claim a 4-2 win at Qarabag to finally open their account in the competition this season.
Victory took them off the bottom of the table and kept alive their slim hopes of making the play-offs, while Villarreal slumped to last position after a 3-2 home defeat to FC Copenhagen.
R.Bernasconi--NZN